October 2018

Does Piperacillin-Tazobactam Measure Up to Meropenem for ESBL Bloodstream Infections?

Extended-spectrum β-lactamase (ESBL)-producing Gram negative bacilli (GNB) have been classified by the CDC as a serious threat in its report Antibiotic Resistance Threats in the United States, 2013.  Based on conservative estimates, ESBL-producing GNB are responsible for at least 26,000 infections and 1,700 deaths annually. While carbapenems (e.g., meropenem, imipenem-cilastatin, doripenem, and ertapenem) are considered… Read More